Research Paper Volume 15, Issue 23 pp 14210—14241
Integrated bioinformatics and experiment revealed that cuproptosis is the potential common pathogenesis of three kinds of primary cardiomyopathy
Figure 15. Effects of three K-CRGs on cuproptosis in AC16 cells. (A–C) The effect of siRNA knockdown on three K-CRGs. (D) The protein expression levels of POLD1, HSP70 and LIAS in AC16 cells after three K-CRGs were knocked down (n = 3). (E) The effects of three K-CRGs knockdown on AC16 cells viability. (F) The effects of three K-CRGs knockdown on copper ion levels in AC16 cells. (G) The protein expression levels of lipoylated DLAT and total DLAT in AC16 cells after three K-CRGs were knocked down (n = 3). (*P < 0.05, **P < 0.01).