Research Paper Volume 15, Issue 23 pp 14086—14108
Transcriptome research of human amniocytes identifies hub genes associated with developmental dysplasia in down syndrome
Figure 3. HSA21-related DEG enrichment. (A) Gene set enrichment analysis (GSEA) of all expressed genes in the “C1:positional” gene sets collection of MSigDB (Broad Institute). Abbreviations: ES: enrichment score; FDR: false discovery rate (adjusted p value). (B) Heatmap of the expression level of the DEGs on HSA21 (blue, low; red, high expression). (C) Enriched GO-BP terms and involved genes of annotated DEGs on HSA21. (D) KEGG disease enrichment analysis of annotated DEGs on HSA21.