Research Paper Volume 15, Issue 23 pp 13998—14018

Modified Chaishao Liujunzi Decoction inhibits bile acid-induced gastric intestinal metaplasia: from network prediction to experimental verification

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Figure 10. MCLD inhibited cell proliferation and GIM through the EGFR/PI3K/AKT/mTOR pathway. (A, B) Western blotting was used to detect the protein expression of EGFR, p-EGFR, PI3K, p-AKT, AKT, mTOR, p-mTOR, Ki67, Cyclin D1, CDX2, and MUC2 in DCA-induced GES-1 cells. Data are expressed as mean±standard deviation (SD) (n=3). Compared with the control group, ### P <0.001; Compared with the DCA group, * P <0.05, **P <0.01, ***P <0.001; Compared with the DCA+NSC228155 group, ^ P <0.05, ^ ^P <0.01, ^ ^ ^P <0.001.