Research Paper Volume 15, Issue 22 pp 13542—13557
Long non-coding RNA EGOT is associated with 131iodine sensitivity and contributes to thyroid cancer progression by targeting miR-641/PTEN axis
Figure 1. The establishment of 131I-resistant TC cells. (A–F) TPC-1 and FTC-133 cells were treated with sub-lethal 131I. (A) The 131I -resistant TPC-1 and FTC-133 cells were established after 8-continuous passages. (B) The cell viability was measured by CCK-8 assays in TPC-1, FTC-133 cells, and 131I -resistant TPC-1 and FTC-133 cells. (C, D) Flow cytometry analysis of cell apoptosis in the cells. (E, F) Western blot analysis of γ-H2AX expression in the cells. mean ± SD, ** P < 0.01. Experiments were repeated at least biological triplicates.