Figure 8. The association of ERS-based signature with the scRNA-seq characteristics. (A) UMAP plot revealed the composition of 10 main clusters derived from PRAD scRNA seq data. (B) The AUC score (activity) of ERS-based signature in 10 main clusters. (C) Circos plots showed inferred ligand-receptor interactions of the high and low ERS score groups. (D) Differences in intercellular interactions (number and strength) of all cells between the high and low score groups. (E–H) Circos plots displayed the differences in EGF, VEGF, PDGF, and IGF signaling pathways between the high and low score groups.