Research Paper Volume 16, Issue 1 pp 43—65

An endoplasmic reticulum stress-related signature featuring ASNS for predicting prognosis and immune landscape in prostate cancer

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Figure 3. The establishment of ERscore and verification of its prognostic efficiency. (A) Univariate Cox regression analysis recognized 47 prognosis-associated genes. (B) Correlations between error rate and classification trees. (C) The relative importance of prognosis-associated genes. (D) The corresponding coefficients of ERscore-constructed genes. (E) The Kaplan-Meier method unveiled a significantly worse BCRF survival of the high-risk cohort compared to the low-risk cohort. (F) The illustrations of all patient’s survival condition, risk variations, and ERscore distributions. (G) ROC approach validated that ERscore was a promising prognostic indicator. (HM) The outcomes of MSKCC and GSE70769 cohorts also validated ERscore’s prognostic value.