Research Paper Volume 15, Issue 22 pp 12763—12779

Effects of paternal and chronological age on BEGAIN methylation and its possible role in autism

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Figure 1. Paternal age effect on BEGAIN promoter methylation in human sperm. Scatter plot showing significant (Pearson’s r = -0.27; p = 0.037) negative correlation between donor age (x-axis in years) and mean methylation of the 9 analyzed CpGs (y-axis in %) in 90 human sperm samples (blue dots).