Research Paper Volume 15, Issue 23 pp 13854—13864
Long noncoding RNA MEG8 induces an imbalance of Th17/Treg cells through the miR-107/STAT3 axis in Henoch-Schonlein purpura rats
Figure 3. Deletion of MEG8 inhibited the differentiation of the Treg population in HSP CD4+ T cells. (A, B) MEG8 expression in the control group transfected with scramble and si-MEG8 was analyzed through qRT-PCR. (C–F) Analysis of Th17/Treg cells, and (G) RT-qPCR examination for RORγt/Foxp3 expression (control group), peripheral blood CD4+ T cells (HSP group), (HSP + scramble) or si-MEG8 (HSP + si- MEG8). *P <0.01 vs. Scramble group; #P <0.01 vs. Control group; ※P <0.01 vs. HSP + Scramble group.