Research Paper Volume 15, Issue 23 pp 13776—13798

Figure 4. Development of a four-gene risk model and its correlation with lncRNA. (A) Correlation analysis between CXCL9, CXCL10, CXCL11, and CXCL13 and lncRNA (cor=0.35, p < 0.05). (B, C) Least Absolute Shrinkage and Selection Operator (LASSO) regression analysis of the 42 differentially expressed mRNAs (DEMs), with 16 selected as valuable prognostic indicators. (D) Receiver operating characteristic (ROC) curve of the four-gene model at 2, 3, and 5 years. (E, F) Comparison of overall survival (OS) and progression-free survival (PFS) between the high- and low-risk groups. (G) Visualization of the associations between the four genes of interest (CXCL9, CXCL10, CXCL11, and CXCL13) and 15 lncRNAs using Cytoscape. (H) Chord plot showing correlations between the four genes and the 15 model lncRNAs.