Figure 4.RFC3 expression is upregulated in tamoxifen-resistant ER-positive breast cancer strains. (A) qPCR results showed that RFC3 mRNA expression was upregulated in MCF-7R tamoxifen-resistant cells. (B) WB results showed that RFC3 protein was upregulated in MCF-7R tamoxifen-resistant cells. (C, D) IHC results showed that RFC3 protein expression was upregulated in pathological tissues of patients with relapse of endocrine therapy.
