Research Paper Volume 15, Issue 23 pp 13738—13752
Involvement of RFC3 in tamoxifen resistance in ER-positive breast cancer through the cell cycle
Figure 4. RFC3 expression is upregulated in tamoxifen-resistant ER-positive breast cancer strains. (A) qPCR results showed that RFC3 mRNA expression was upregulated in MCF-7R tamoxifen-resistant cells. (B) WB results showed that RFC3 protein was upregulated in MCF-7R tamoxifen-resistant cells. (C, D) IHC results showed that RFC3 protein expression was upregulated in pathological tissues of patients with relapse of endocrine therapy.