Research Paper Volume 15, Issue 22 pp 13486—13503
The ferroptosis landscape in acute myeloid leukemia
Figure 5. The relationship between AIFM2 expression and the mutation frequency of related genes, including NPM1, DNMT3A, FLT3, IDH1, and IDH2 (A). Methylation at the DNA promoters of AIFM2 in the FAB subtype (B). The correlation of AIFM2 expression levels and methylation (C). The relationship between GPX4 expression and the mutation frequency of related genes, including NPM1, DNMT3A, FLT3, IDH1, and IDH2 (D). Methylation at the DNA promoters of GPX4 in the FAB subtype (E). The correlation of GPX4 expression levels and methylation (F).