Research Paper Volume 15, Issue 23 pp 13693—13709
The antioxidant Glycitin protects against intervertebral disc degeneration through antagonizing inflammation and oxidative stress in nucleus pulposus cells
Figure 5. Glycitin alleviated the degeneration of IVD in rats in vivo. (A) Schematic diagram of needle puncture model of rat. (B, C) MRI image was used to assess the signal strength of IVDD in rats from every group (n = 3). (D, E) X-ray was applied to evaluate the height of the intervertebral space in rats from each group (n = 3). (F–I) HE, Safranin-O and Masson staining were conducted to evaluate the IVDs in rats from every group (n=3). Histological score was obtained from staining data. Scale bar: 100 μm. The values represent the mean ± SD of three independent experiments. *p < 0.05 vs. control group.