Research Paper Volume 15, Issue 22 pp 13411—13421

Regulatory mechanisms of miR-212-3p on the secretion of inflammatory factors in monocyte-macrophages and the directed differentiation into osteoclasts in ankylosing spondylitis

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Figure 1. (A) GSE11886 pictures of the database prior to the quantitative normalization. (B) The GSE11886 dataset was screened according to P<0.05, |logFC|<1. The results showed that there were 263 DEGs in ankylosing spondylitis mRNA, of which 149 were up-regulated and 114 were down-regulated. The volcano map of dataset GSE11886 was constructed in R software using ggplot2 software package. (C) Images of GSE118806 data set after standardized processing. (D) Volcano map of the GSE118806 dataset. (E) Image after quantitative standardization processing of the GSE11886 database. (F) Pheatmap software package in R software was used to draw DEGs cluster analysis heatmap. (G) Images after standardized processing of the GSE118806 dataset. (H) Clustering heat map of the GSE118806 dataset.