Figure 6. Aged EVs impact migration of young keratinocytes in 2D culture. Confluent young keratinocytes cultures were scratch wounded and exposed to young or old keratinocytes EVs for 40 h. The remaining wound area were quantified at 24 h and 40 h by ImageJ from triplicate experiments (*p-value < 0.05. **p-value < 0.01. Student’s t-test).