Research Paper Volume 15, Issue 22 pp 13329—13344

Figure 3. Knockdown of circSLCO1B7 promoted the progression of HCC cells. (A) qRT–PCR measured the knockdown efficiency of circSLCO1B7 in Li-7 cells transfected with si-NC, si1 and si2. (B) The CCK-8 assay was used to detect the proliferation ability of transfected Li-7 cells. (C) The migration and invasion ability of transfected Li-7 cells were measured by Transwell assay. (D) A wound healing assay was performed to detect the migration levels of transfected Li-7 cells. (E, F) The apoptosis rate (E) and distribution of the cell cycle (F) in transfected Li-7 cells were analysed by flow cytometry. All data are presented as the means ± SD. ^*P < 0.05, ^**P < 0.01, ^***P < 0.001, ^****P < 0.0001.