Research Paper Volume 15, Issue 22 pp 13213—13238

A prognostic risk model for programmed cell death and revealing TRIB3 as a promising apoptosis suppressor in renal cell carcinoma

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Figure 7. Mechanisms of PRPCDGs risk signature in KIRC. (A) Heatmap of correlations between PRPCDGs risk signature expression and their activity scores of cancer-associated hallmark pathways. (B) Network diagram of the correlations between PRPCDGs’ expression and its highly correlated KEGG pathways. (C) Heatmap of activities of 7 metabolic pathways in high- or low-PRPCDGs-risk group from TCGA-KIRC database. (D) Heatmap of correlations between the PRPCDGs risk signature and 7 metabolic pathways in two different risk groups from KIRC database.