Figure 9. IBSP knockdown inhibits cell proliferation. (A) The IBSP expression in normal cell lines including HaCaT and HOB, and osteosarcoma cells including SaOS2, U2-OS, and MG-63. (B) The knockdown efficiency. (C) The overexpression efficiency. (D) The CCK-8 assay showing cell proliferation. (E) The colony formation assay showing cell proliferation. Abbreviation: NS: no significance. *P < 0.05, **P < 0.01.