Research Paper Volume 15, Issue 22 pp 12749—12762

Figure 4. NecB suppressed the developmental eye defects in D. melanogaster. (A) Oregon-RC males, (B) Oregon-RC females, (C) DGRP-100 males and (D) DGRP-100 females. Ctrl represents standard cornmeal medium; Rap-50 represents cornmeal medium supplemented with Rapamycin at 50 μg/mL; Rap-200 represents cornmeal medium supplemented with Rapamycin at 200 μg/mL; NecB-50 represents cornmeal medium supplemented with NecB at 50 μg/mL; and NecB-200 represents cornmeal medium supplemented with NecB at 200 μg/mL (Supplementary Table 1). Light microscopy studies of the Drosophila compound eyes were performed at the 30th, 60th and 90th days post-eclosion, and the eye damages are indicated as arrows.