Atorvastatin mitigates memory deficits and brain monocyte infiltration in chronic hypercholesterolemia

Fengchao Gong; Qian Shi; Xiaojie Mou; Kang Wang; Qianqian Wang; Haitao Wang

doi:doi:10.18632/aging.205217

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Research Paper Volume 15, Issue 23 pp 13669—13679

Atorvastatin mitigates memory deficits and brain monocyte infiltration in chronic hypercholesterolemia

Figure 3. Atorvastatin repressed the monocyte infiltration in aged ApoE^-/- mice. (A) The percentage of brain Ly6C^hi cells (%CD45⁺ viable cells) was detected by flow cytometry; (B) The percentage of brain CD3⁺ cells (%CD45⁺ viable cells) was detected by flow cytometry (*, **, P<0.05, 0.01 vs. vehicle; #, P<0.05 vs. ApoE^-/- mice group).