Integrated analysis of single-cell RNA-seq and bulk RNA-seq unravels the heterogeneity of cancer-associated fibroblasts in TNBC

Xiaoqing Wu; Wenping Lu; Weixuan Zhang; Dongni Zhang; Heting Mei; Mengfan Zhang; Yongjia Cui; Zhili Zhuo

doi:doi:10.18632/aging.205205

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Research Paper Volume 15, Issue 21 pp 12674—12697

Integrated analysis of single-cell RNA-seq and bulk RNA-seq unravels the heterogeneity of cancer-associated fibroblasts in TNBC

Figure 9. Analysis of CAF-related genes between molecular subtypes. (A) The expression of immune checkpoint-related genes among clusters. (B–D) The expression of checkpoint-related genes associated with survival in triple-negative breast cancer patients. (E, F) ROC curves for the training and testing sets. (G) Nomogram predicting patient survival prognosis. (H) Calibration curve of the nomogram.