Research Paper Volume 15, Issue 21 pp 12674—12697

Integrated analysis of single-cell RNA-seq and bulk RNA-seq unravels the heterogeneity of cancer-associated fibroblasts in TNBC

class="figure-viewer-img"

Figure 2. Normalization and quality control of scRNA-seq. (A) Single-cell sequencing depth, counts and fraction of reads mapped to mitochondrial genes in TNBC samples. (B) Single-cell sequencing depth, counts and fraction of reads mapped to mitochondrial genes in breast tissues. (C) Correlation of gene count and percent of mitochondrial genes and features in TNBC. (D) Correlation of gene count and percent of mitochondrial genes and features in breast tissue. (E) The first 1500 genes were screened as variant genes in TNBC samples. (F) The first 1500 genes were screened as variant genes in normal breast.