Research Paper Volume 15, Issue 21 pp 12633—12650
KIFC1 promotes proliferation and pseudo-bipolar division of ESCC through the transportation of Aurora B kinase
Figure 6. KIFC1 regulates the expression and subcellular localization of Aurora B. (A) The subcellular localization of Aurora B after overexpression and knockdown of KIFC1, where Aurora B is indicated in red, and gamma tubulin in green; (B) Protein levels of Aurora B and the expression and phosphorylation of its substrate Histone H3 after overexpression and knockdown of KIFC1; (C) co-IP detect the binding of Aurora B and Histone H3; (D) The molecular docking model of KIFC1 with Aurora B-INCENP complex.