Research Paper Volume 15, Issue 21 pp 12633—12650
KIFC1 promotes proliferation and pseudo-bipolar division of ESCC through the transportation of Aurora B kinase
Figure 2. Bioinformatics analysis of signaling pathways associated with KIFC1. (A) Heatmap of gene expression by grouping TCGA samples based on the level of KIFC1 expression; (B) Volcano plot of differential genes between the top 25% of samples with high KIFC1 expression and the bottom 25% of samples with low KIFC1 expression; (C) Clustering analysis of upregulated differentially expressed genes in the top 25% of samples with high KIFC1 expression; (D) Network of enriched term; (E–H) Correlation analysis of KIFC1 expression with tumor proliferation, G2/M checkpoints, DNA replication, and the p53 pathway.