Research Paper Volume 15, Issue 21 pp 12588—12617
Characterization of the immune cell function landscape in head and neck squamous carcinoma to assist in prognosis prediction and immunotherapy
Figure 6. Identification and validation of the key target and prediction of candidate small molecule compounds. (A) The PPI network of the ICF gene signature (interaction score ≥ 0.4). (B) The expression analysis of CD247 in control mucosal epithelia cells and HNSCC cell lines. (C) IHC staining of CD247 in HNSCC tissues. (D) Kaplan-Meier survival analysis of HNSCC patients according to CD247 IHC scores. The molecular docking diagram shows the interaction between the small molecules Eltrombopag (E), ZINC116473771 (F), and Conivaptan (G) with CD247.