Figure 7. Biological processes associated with genomic stability and proteostasis are downregulated in the ovary with age. GO analysis of proteins significantly downregulated with age from (A) native and (B) ECM-enriched ovaries was performed using consensus pathway database (CPDB) at level 4, q-value < 0.05. The level of enrichment (corrected gene ratio) is depicted from 0–1, corresponding to 0–100% enrichment of the listed pathway.