Research Paper Volume 15, Issue 21 pp 12275—12295
Identification of M5c regulator-medicated methylation modification patterns for prognosis and immune microenvironment in glioma
Figure 3. Obtaining consensus clusters by m5c regulators. (A) The relationship between cophenetic, dispersion, evar, residuals, rss and silhouette coefficients with respect to number of clusters. (B) The consensus map of NMF clusterin in the total TCGA cohort. Patients were clustered into subgroups based on the expression of 13 m5c regulators. (C) Principal component analysis for the expression profiles of 13 m5c regulators to distinguish different cluster. (D) The survival curve in cluster 1 and 2. (E) The correlation analysis of m5c regulators and clinical phenotypes in cluster 1 and 2.