Research Paper Volume 15, Issue 21 pp 12225—12250

Plumbagin has an inhibitory effect on the growth of TSCC PDX model and it enhances the anticancer efficacy of cisplatin

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Figure 6. Administration of plumbagin affected Akt/mTOR expression in TSCC PDX models. (A) The expression level of AKT, p-AKT, mTOR and p-mTOR were measured by Western blotting. (B) The histograms indicate the relative expression levels of p-AKT/AKT, p-mTOR/mTOR. The quantitative data are shown as the mean ± SD of 3 independent experiments. ***P < 0.001, **P < 0.01 and −, no statistical difference.