Research Paper Volume 15, Issue 21 pp 12209—12224

Effects of amyloid β (Aβ)42 and Gasdermin D on the progression of Alzheimer’s disease in vitro and in vivo through the regulation of astrocyte pyroptosis

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Figure 5. Inhibition of astrocyte pyroptosis can alleviate brain tissue lesions in APP/PS1 mice. (A) H&E staining of brain tissues. (B) Immunohistochemical analysis and protein expression of each group of GFAP, Aβ, IL-1β, IL-18, tau, and tunnel.