Hepatoprotective effect of syringin combined with costunolide against LPS-induced acute liver injury in L-02 cells via Rac1/AKT/NF-κB signaling pathway

Jingxin Mao; Lihong Tan; Cheng Tian; Wenxiang Wang; Hao Zhang; Zhaojing Zhu; Yan Li

doi:doi:10.18632/aging.205161

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Research Paper Volume 15, Issue 21 pp 11994—12020

Hepatoprotective effect of syringin combined with costunolide against LPS-induced acute liver injury in L-02 cells via Rac1/AKT/NF-κB signaling pathway

Figure 7. (A) Effects of syr+cos on inflammatory pathway, cell cycle and apoptosis-related proteins respectively. (B) Effects of syr+cos on NF-κB related signaling pathway. (C) Effects of syr+cos on p65 (nucleus) and p65 (cytosol). Note: The data represent the mean ± SD (n = 5) per group. ^**P < 0.01 vs control group; ^##P < 0.01 vs LPS treatment group.