Research Paper Volume 15, Issue 21 pp 11970—11984
Identification of epithelial-mesenchymal transition-related biomarkers in lung adenocarcinoma using bioinformatics and lab experiments
Figure 3. Clinical significance of the eight-gene signature. (A–D) The low-risk group had a better survival time as compared with the high-risk group in the TCGA cohort, the GSE8894 cohort, the GSE50081 cohort, and the GSE30219 cohort. (E–G) The levels of risk score were significantly augmented in patients with higher TNM staging. (H) Risk score was negatively correlated with immune score (P = 0.0017, R = -0.1398). (I–L) Multiple biological processes related to tumor progression were significantly enriched, including DNA replication, cell cycle, chromosome segregation, and nuclear division.