Research Paper Volume 15, Issue 20 pp 11654—11671

PCMT1 regulates the migration, invasion, and apoptosis of prostate cancer through modulating the PI3K/AKT/GSK-3β pathway

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Figure 7. PI3K activator 740Y-P can reverse the effect of siRNA-PCMT1 on the migration, invasion, and apoptosis of PCa cell lines. (A) The migration ability of PCa cells was measured by a transwell migration assay (×200). (B) The invasion ability of PCa cells was measured by a transwell invasion assay (×200). (C) The apoptotic rate of PCa cells was measured by a flow cytomet assay. Data are expressed as mean ± SD of at least three experiments. ***P < 0. 001.