Research Paper Volume 15, Issue 20 pp 11588—11610
Immunobiological signatures and the emerging role of SPP1 in predicting tumor heterogeneity, malignancy, and clinical outcomes in stomach adenocarcinoma
Figure 8. Tumor microenvironment characteristics (TME) analysis. (A) The clinical correlation analysis showing the number and percentage of patients with each clinical trait in the high- and low-risk groups. (B) Immune cell infiltration analysis. (C) Analysis of tumor microenvironment differences. *** indicating that tumor microenvironment scores are different between high- and low-risk groups. (D) Analysis of immune cell abundance and gene correlation degree. ***p < 0.001; **p < 0.01; *p < 0.05. Blue showed a negative correlation, red showed a positive correlation. (E, F) Risk score and DNA, RNA stemness analysis. Analysis of differences in scores of CAF and other TME populations in high- and low-risk groups. (G) Risk score divided differential immune exclusion cells and cancer-associated fibroblasts (CAFs) abundance.