Research Paper Volume 15, Issue 21 pp 11860—11874
Lipid reprogramming induced by the NNMT-ABCA1 axis enhanced membrane fluidity to promote endometrial cancer progression
Figure 3. NNMT promotes migration and invasion by reducing cholesterol in EC cells. (A) Intracellular cholesterol levels detected by Amplex® Red cholesterol assay. (B, C) Representative results of Dil-C16 staining and fluorescence recovery recordings using confocal microscopy. (D) Representative results of cholesterol-treated wound healing assay. (E) Representative results of migration and invasion assays under cholesterol treatment (Scale: 100 μm). (*P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001, NS = not significant).