Research Paper Volume 15, Issue 20 pp 11489—11507
Anti-cancer targets and molecular mechanisms of formononetin in treating osteosarcoma based on network pharmacology
Figure 11. (A) Western blotting results showing expression of cleaved caspase-3, p21, and p53. Formononetin inhibited bcl-2 expression (B) and induced the expression of cleaved caspase-3 (C) through the p21/p53 (D, E) pathway and inhibited the expression of SATB2 (F). Data are presented are the means ± SD of three independent experiments. *p < 0.01 vs. control group.