Research Paper Volume 15, Issue 24 pp 14617—14650

Figure 2. Correlation between immune cell infiltration and TRIM28 in HCC. (A) The quantity of immune cells (T cell CD8, T cell CD4, B cell, Macrophage, Neutrophil and Myeloid dendritic cell) in HCC with altered TRIM28 copy numbers from TIMER 2.0 database. (B) Kaplan-Meier plots were used to analyze the TRIM28-binding immune infiltration and overall survival rate of HCC. Among these, T cell CD4 (0.036), Macrophage (0.007) and Neutrophil (0.01) markedly positively correlated with infiltrating levels. (C, D). Immune cells levels were showed in a heatmap and lollipop diagrams from TCGA. (E) The immune genes associated TRIM28 expression level analysis from TCGA. Log2 (TPM + 1) was applied for log-scale. ^*p < 0.05; ^***p < 0.001. Abbreviation: ns: no significant.