Research Paper Volume 15, Issue 20 pp 11471—11488

Figure 2. LiCl reverses the inactivation of Wnt pathway, increases osteogenic capacity, and reduces apoptosis levels in OVX mice. (A–K) Western blotting and quantification of TERT, β-catenin, p-GSK3β/GSK3β, OPN, Runx2, BMP2, Bcl-2, and BAX expression levels in the sham, OVX, and OVX+LiCl group mice. (L) ALP activity detected by ALP activity assay kit in three groups of mice. (M, N) The representative pictures of immunofluorescence staining (original magnification, ×400) and their analyses showed the expressions of BMP2 and TERT in mice femurs. All results are performed as mean ± SD. ^#P < 0.05, ^##P < 0.01 vs. control group, ^*P < 0.05, ^**P < 0.01, ^***P < 0.005 vs. OVX group, n = 6.