Research Paper Volume 15, Issue 20 pp 11412—11447

Molecular characterization of ferroptosis in soft tissue sarcoma constructs a prognostic and immunotherapeutic signature through experimental and bioinformatics analyses

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Figure 9. The Fescore predicted immune response in immunotherapy datasets. (A) Survival plot of high and low Fescore in IMvigor210 dataset (p = 0.0027). (B) Relative percent of immune responses in high and low Fescore in IMvigor210 dataset. Abbreviations: CR: complete response; PR: partial response; SD: stable disease; PD: progressive disease. (C) Relative percent of CR/PR and SD/PD in high and low Fescore in IMvigor210 dataset. (D) ROC curve for prediction of immune response in IMvigor210 dataset. (E) Survival plot of high and low Fescore in GSE78220 dataset (p = 0.17). (F) Relative percent of immune responses in high and low Fescore in GSE78220 dataset. Abbreviations: CR: complete response; PR: partial response; PD: progressive disease. (G) Relative percent of CR/PR and SD/PD in high and low Fescore in GSE78220 dataset. (H) ROC curve for prediction of immune response in GSE78220 dataset. (I) ROC curve for prediction of immune response in GSE35640 dataset. (J) Relative percent of CR/PR and SD/PD in high and low Fescore in GSE35640 dataset.