Research Paper Volume 15, Issue 20 pp 11268—11285
Integrated bulk and scRNA sequence identified anoikis-related diagnostic biomarkers and potential association with immune infiltration in type A aortic dissection
Figure 3. Identification of diagnostic ARGs and ROC evaluation for TAAD patients. (A) Veen plots identified 31 up-regulated and 20 down-regulated differential ARGs. (B) The expression of differential ARGs between TAAD and HC tissues in heatmaps. (C, D) The KEGG functional analysis of up-regulated and downregulated differential ARGs. (E) The results of LASSO regression screening the eight diagnostic ARGs for TAAD. (F) The ROC analysis revealed that these diagnostic ARGs exhibited prominent diagnostic efficiency for TAAD patients with high AUC values including CHEK2/0.95, HIF1A/0.99, HK2/0.99, HMGA1/0.95, SERPINA1/0.98, PTPN1/0.98, SLC2A1/0.86 and VEGFA/1.0.