Figure 12. The roles of CDKN2A in oncogenesis and drug sensitivity. (A) Importance analysis displayed CDKN2A ranked top 1 in XGboost-mediated CRG subgroup identification. (B) The expression level of CDKN2A in pan-cancer. (C) IHC of CDKN2A in the breast cancer tissues and adjacent tissues (THPA: https://www.proteinatlas.org). (D) The mRNA expression level of CDKN2A in subtypes of breast cancer (UALCAN: http://ualcan.path.uab.edu/tutorial.html). (E) IHC of CDKN2A from local breast cancer. (F) The relationship between CDKN2A and clinical stage. (G) The relationship between drug score and the expression of CDKN2A.