Research Paper Volume 15, Issue 20 pp 11217—11226

Identification of cellular senescence-related signature for predicting prognosis and therapeutic response of acute myeloid leukemia

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Figure 2. The expression variation landscape and prognostic analysis of cellular senescence-related genes (CSRGs). (A, B) Somatic mutation characteristics of high and low CS-score groups. (A) High CS-score group; (B) low CS-score group. (C) Differences in expression of cellular senescence-induced genes between AML and normal samples. (D) Differences in expression of cellular senescence-inhibited genes between AML and normal samples. (E) Identification of CSRGs significantly related to the prognosis of AML patients. *P < 0.05, **P < 0.01, ***P < 0.001.