Research Paper Volume 15, Issue 20 pp 11152—11161
The novel GLP-1/GIP dual agonist DA3-CH improves rat type 2 diabetes through activating AMPK/ACC signaling pathway
Figure 2. Significant tissue injury and apoptosis in pancreatic tissues of T2DM rats were inhibited by DA3-CH. (A) HE staining was performed to investigate the influence of DA3-CH on pancreatic tissue injury in vivo; (B) Tunel staining was performed to investigate the influence of DA3-CH on apoptosis level in vivo; (C) The staining intensity was analyzed; (D) IHC staining was performed to investigate the influence of DA3-CH on Bax expression in vivo; (E) The staining intensity was analyzed; * means p <0.05. n=5 for each group.