Research Paper Volume 15, Issue 19 pp 10627—10639

Evaluation of time-dependent phenotypes of myocardial ischemia-reperfusion in mice

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Figure 4. Dynamic changes in serum inflammatory cytokines following reperfusion. (A) Serum inflammatory cytokines concentrations of TNF-α. (B) Serum inflammatory cytokines concentrations of IL-6. (C) Serum inflammatory cytokines concentrations of IL-1β (n = 3 : 3 : 3 : 3). (D) Representative western blot and (E, F) statistical data of myocardium inflammation by detection of IL-10 and TLR4 expression levels in mouse hearts treated as indicated (n = 3 : 3 : 3 : 3). MI=Myocardial infarction, Rep=reperfusion. Data are shown as mean ± SD. One-way ANOVA followed by Tukey post hoc test was used for statistical comparisons between multiple groups. *P < 0.05; **P < 0.01; ***P < 0.001.