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Research Paper Volume 15, Issue 18 pp 9877—9889

Myeloid-specific knockout of SHP2 regulates PI3K/PLCγ signaling pathway to protect against early myocardial infarction injury

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Figure 1. SHP2MAC-KO improves the cardiac function in mice with myocardial infarction. (A) Ultrasound imaging of mice in sham: SHP2WT group, sham: SHP2MAC-KO group, Model: SHP2WT group and Model: SHP2MAC-KO mice; (B) Statistics of EF, FS, LVAW; d, LVAW; s, LVID; d and LVID; s. P<0.01, ns P>0.05.