Figure 6. Development of a novel nomogram integrating the risk signature and several clinicopathologic features. (A) Results of univariate Cox regression analysis based on risk score and clinicopathologic features. (B) Results of multivariate Cox regression analysis based on risk score and clinicopathologic features. (C) Construction of the nomogram integrating the T, N-stage and risk score. (D) Decision curve for nomogram. (E) Calibration curves for 1, 2, and 3 years of nomogram. (*P < 0.05; **P < 0.01; ***P < 0.001).