Research Paper Volume 15, Issue 19 pp 10501—10523

A SARS-CoV-2 related signature that explores the tumor microenvironment and predicts immunotherapy response in esophageal squamous cell cancer

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Figure 5. A novel risk signature constructed based on several SCRGs. (A) Volcano plot of differentially expressed genes between tumor and normal samples in GSE53624 cohort. Volcano plot of prognosis-correlated genes obtained by univariate Cox regression analysis. (B) Each independent variable’s trajectory and distributions for the lambda. (C) The multivariate Cox coefficients for each gene in the risk signature. (D) Circle plot showing each gene in the risk signature. (E) K-M and ROC curves of the risk signature in GSE53624 cohort. (F) K-M and ROC curves of the risk signature in TCGA cohort.