Research Paper Volume 15, Issue 19 pp 10501—10523
A SARS-CoV-2 related signature that explores the tumor microenvironment and predicts immunotherapy response in esophageal squamous cell cancer
Figure 2. The identification of SCRGs clusters according to scRNA data of ESCC patients. (A) tSNE plots of distribution of 32 clusters and SARS-CoV-2 marker genes expression. (B) tSNE plots of distributions of eight fibroblasts after clustering. (C) tSNE distribution of malignant and non-malignant cells predicted by copycat package. (D) Subgroups in cancer and adjacent tissue and proportion as well as cell number calculation. (E) Bubble diagram of the top5 marker gene expression of subgroups. (F) Volcano plot of the top5 marker gene expression of subgroups.