Research Paper Volume 15, Issue 19 pp 10370—10388
Bridging the gap between clear cell renal cell carcinoma and cutaneous melanoma: the role of SCARB1 in dysregulated cholesterol metabolism
Figure 8. Exploration of the expression and prognostic ability of SCARB1 in SKCM. (A–C) Differential mRNA expression analysis of SCARB1 between cutaneous melanoma and normal skin tissues from the GEO database, including (A) GSE46517, (B) GSE15605, and (C) GSE3189. (D–F) The K-M survival curves showing the poorer survival probability of SKCM patients in the high-SCARB1 group with different observation end points, including (D) overall survival, (E) disease specific survival, and (F) progress free interval. (G–I) Differential mRNA expression analysis of SCARB1 between SKCM patients stratified by classic prognostic predictors, including (G) pathologic T stage, (H) Clark level, and (I) Breslow depth. *p-value < 0.05, **p-value < 0.01, ***p-value < 0.001.