Research Paper Volume 15, Issue 19 pp 10370—10388

Bridging the gap between clear cell renal cell carcinoma and cutaneous melanoma: the role of SCARB1 in dysregulated cholesterol metabolism

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Figure 7. Pancancer analysis of cholesterol-resource related gene expression. (AE) Differential mRNA expression analysis of (A) HMGCS1, (B) HMGCR, (C) SREBF2, (D) LDLR, and (E) SCARB1 between malignant tumor and corresponding adjacent tissues. (F) The heatmap showing the differences in the expression of each cholesterol-resource related gene in each malignant tumor and corresponding adjacent tissues. Abbreviations: T > N: The gene expression in the tumor is higher than the adjacent tissue; T < N: The gene expression in the tumor is lower than the adjacent tissue. *p-value < 0.05, **p-value < 0.01, ***p-value < 0.001.