Research Paper Volume 15, Issue 19 pp 10347—10369
Mitochondrial-related genes markers that predict survival in patients with head and neck squamous cell carcinoma affect immunomodulation through hypoxia, glycolysis, and angiogenesis pathways
Figure 1. Molecular typing based on mitochondrial-related genes. (A) Identification of differential mitochondria-related genes with significant prognosis; (B) Expression of 39 genes in tumor and paraneoplastic normal samples; (C) CDF curves of TCGA cohort samples; (D) CDF Delta area curves of TCGA cohort samples, Delta area curve of consensus clustering, indicating the relative change in area under the cumulative distribution function (CDF) curve for each category number k compared with k – 1. The horizontal axis represents the category number k, and the vertical axis represents the relative change in area under the CDF curve; (E) Heat map of sample clustering at consensus k = 3; (F) KM curves of the relationship among the prognosis of the three subtypes of TCGA; (G) KM curves of the prognosis of the three subtypes in the GSE41613 cohort.