Research Paper Volume 15, Issue 19 pp 10322—10346

Analysis and experimental validation of fatty acid metabolism-related genes prostacyclin synthase (PTGIS) in endometrial cancer

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Figure 8. PTGIS regulates the biological behavior of EC cell lines and in vivo study of tumor xenografts. (A) Cell apoptosis assay was used to determine the effect of PTGIS on the apoptosis of Ishikawa and HEC-1A cell lines. (B) Cell cycle analysis was used to detect the effect of PTGIS on the cell cycle of Ishikawa and HEC-1A cell lines. (C) The nude mice carrying tumors from the respective groups are shown. The sample tumors from the respective groups are shown (n = 3, each group). (D) Expression levels of Ki-67.